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Best aspirins - September 2025

Last Updated - September 26, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bayer

Bayer Extra Strength 500mg Aspirin Plus Caffeine for Powerful Pain Relief, 200 Coated Caplets

Bayer

$17.17

More Details
Main highlights
- Targeted Back and Body Relief: Bayer Back and Body Extra Strength Aspirin provides fast, proven relief of backache and muscle aches and pains
- Powerful Pain Reliever: Dual action formula containing aspirin and caffeine for a pain relief booster provides fast relief at the site of pain, when taken as directed
- Free From: Each coated pain medicine tablet is free of sodium and is coated to make it easier for swallowing
- Aspirin Plus Caffeine: This pain medicine for adults and children over 12 contains 500mg aspirin, as well as 32.5mg caffeine to help boost the pain-relieving effects of aspirin
- 125 Years of Relief: Bayer Aspirin has been a leading aspirin brand in pain relief
$17.17
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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bayer

Bayer Genuine Aspirin 325 mg, Pain Reliever and Fever Reducer, Head, Muscle, Minor Arthritis, Back, Tooth, and Menstrual Pain, 300 Coated Tablets

Bayer

$16.79

More Details
Main highlights
- Multi-Symptom Pain Reliever and Fever Reducer: Genuine Bayer Aspirin provides proven relief of headache, backache, muscle pain, toothache, menstrual pain, as well as minor arthritis pain relief, and reduces fever
- Helps Prevent Another Heart Attack or Ischemic Stroke: Genuine Bayer Aspirin can help prevent another heart attack or clot-related (ischemic) stroke
- Free From: Each pain medicine tablet is free of caffeine and sodium and is coated to make it easier for swallowing
- Aspirin is not appropriate for everyone, so be sure to talk to your doctor before you begin an aspirin regimen
- 325 Mg Per Tablet: Each coated tablet of Genuine Bayer Aspirin contains 325 mg of the active ingredient aspirin (NSAID)*
- 125 Years of Relief: Bayer Aspirin has been a leading aspirin brand in pain relief
$16.79
3

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bayer

Bayer Aspirin Low Dose 81 mg, Enteric Coated Tablets, Doctor Recommended, Secondary Prevention of Cardiovascular Disease, 300 Safety Coated Tablets

Bayer

$14.97

More Details
Main highlights
- Relieves Minor Aches and Pains: 81mg aspirin can also be taken for temporary relief of minor body aches and pains
- Protect Your Heart: Bayer Aspirin Low Dose can be used by adults whose doctors recommend a low dose aspirin regimen
- Leading Aspirin Brand: Bayer Aspirin has been a leading brand for second cardiovascular prevention
- Easy to Swallow: Each safety coated 81mg aspirin tablet is coated for easier swallowing and stomach protection, and is also caffeine and sodium-free
- Aspirin is not appropriate for everyone, so be sure to talk to your doctor before you begin an aspirin regimen
- #1 Doctor Recommended: Bayer Aspirin is the #1 doctor recommended aspirin brand
$14.97
4

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

HealthA2Z

HealthA2Z® Aspirin 81 mg | Low Strength | Enteric Coated | Pain Relief | Reduces Minor Aches Muscle Pain & Cramps | Fever Reducer | Reduces Headache (365 Counts)

HealthA2Z

$8.35

More Details
Main highlights
- Its special coating is to make it easier to swallow and formulated to dissolve slowly, providing long term release as opposed to an immediate pain relief product
- Aspirin is not appropriate for everyone, so be sure to talk to your doctor before you begin an aspirin regimen
$8.35
5
Best Value
12% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

PHARBEST
12% Off

PHARBEST Aspirin 325 mg | Regular Strength | 1000 Count Uncoated Tablets

PHARBEST

$12.94

$14.85
(12% Off)

More Details
Main highlights
- Relief from Pain and Fever: Like Bayer Aspirin, it is designed to provide relief from pain and reduce fever, making it suitable for various conditions.
- Manufactured in the USA: Both products are manufactured in the USA, meeting quality standards and assuring consumers of their reliability and safety.
- Generous Supply: With 1000 uncoated tablets per supply, it ensures long-lasting relief for individuals seeking pain relief over an extended period.
- Cost-Effective Alternative: While Genuine Bayer Aspirin may carry brand name recognition, the comparison product offers a cost-effective alternative with identical active ingredients and efficacy.
- Comparable Formulation: The product being compared to Genuine Bayer Aspirin contains Regular Strength Aspirin at 325 mg per tablet, offering a comparable formulation for pain relief and fever reduction.
$12.94
$14.85 (12% Off)

Best aspirins - September 2025

Bayer Extra Strength 500mg Aspirin Plus Caffeine for Powerful Pain Relief, 200 Coated Caplets

Bayer Genuine Aspirin 325 mg, Pain Reliever and Fever Reducer, Head, Muscle, Minor Arthritis, Back, Tooth, and Menstrual Pain, 300 Coated Tablets

Bayer Aspirin Low Dose 81 mg, Enteric Coated Tablets, Doctor Recommended, Secondary Prevention of Cardiovascular Disease, 300 Safety Coated Tablets

HealthA2Z® Aspirin 81 mg | Low Strength | Enteric Coated | Pain Relief | Reduces Minor Aches Muscle Pain & Cramps | Fever Reducer | Reduces Headache (365 Counts)

PHARBEST Aspirin 325 mg | Regular Strength | 1000 Count Uncoated Tablets

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